Research

The Department of Obstetrics, Gynecology and Women's Health at Saint Louis University School of Medicine conducts basic science and clinical research in the areas of general obstetrics and gynecology, women's wellness, gynecologic oncology, urogynecology, reproductive medicine and infertility, and biochemistry, cell biology, and molecular biology. The Department faculty participates in translational research, which helps facilitate the bridge between basic bench research and the delivery of clinical treatments to patients. Currently there are several on-going studies that are recruiting subjects. Below is a listing of the current research being conducted by our faculty.


The Research Division
Faculty Members:

Raul Artal, M. D.
Professor and Chairman
Director,Residency Program

 

    CURRENT RESEARCH ACTIVITY:
  • Diabetes Mellitus and pregnancy
  • Exercise in pregnancy and clinical applications
  • Premature labor etimology and management
  • Detection of cervical dilatation
  • Obesity and body composition
  • Pathophysiology of chorioamniotic membranes
  • Dacorin - collogen intersection
Robert Blaskiewicz, M.D.
Professor and Director,
General OB/GYN
Assistant Director,
Residency Program

 

    CURRENT RESEARCH ACTIVITY:
  • Perceived and actual medical risk in older women.
  • Complementary and alternative medicine use in pregnant and non-pregnant patients.
  • Incidence of uterine hyperstimulation in term patients.
  • Development of an electric toolbox for use in an ambulatory setting.
  • Rates of hysterectomy (1985-1989 and 1995-1999)
  • Thrombophlebitis in patients with preterm labor
  • Risk of uterine rupture in diabetics
  • Evaluation of methods to assess professionalism in medical students
  • Changes in medical student perceptions of the pharmaceutical industry during medical school
Amy A. Flick, M. D.
Assistant Professor
Division Maternal-Fetal Medicine
    CURRENT RESEARCH ACTIVITY:
  • Diabetes
  • Obesity
Jennifer Goldkamp, M.D.
Instructor
    CURRENT RESEARCH ACTIVITY:
  • Barometric Pressure Changes and its Effects on Rupture of Membranes at Term
  • Effects of steroid administration of maternal glucose levels. Ongoing research
  • Diabetes in pregnancy
Gilad A. Gross, M. D.
Professor Director, Division Maternal-Fetal Medicine
    CURRENT RESEARCH ACTIVITY:
  • All aspects of perinatal medicine
  • Critical and operative obstetrical emergency care
  • Development of clinical paths and guidelines
  • Preterm labor
  • Perinatal infections
  • Fetal lung maturity
  • Fetal umbilical cord blood transfusion
  • Lead poisoning prevention
Susan Hoffstetter, Ph.D., WHNP-BC
Associate Professor
Division of Urogynecology
CURRENT RESEARCH ACTIVITY:
Vulvovaginal Diseases:
  • Vulvodynia
  • Vulvar dystrophy
  • Managing lichen sclerosus with mid potency corticosteroids
Mary Brigid Holloran-Schwartz, M.D.
Associate Professor
Section Director, Center of Minimally Invasive Gynecologic Surgery, (MIGS)
    CURRENT RESEARCH ACTIVITY:
  • Minimally invasive gynecologic surgery including laparoscopic hysterectomy, myomectomy,robotic surgery and operative hysteroscopy
  • Gynecologic surgery
  • Endometriosis
  • Abnormal uterine bleeding, uterine fibroids, postmenopausal bleeding, dysmenorrhea and alternatives to hysterectomy
  • Menopause
  • Resident and medical student education
  • Predictor Factors for Difficulty of TLH
  • Prospective Study Comparing Disposable Vessel Sealing Device & Reusable Bipolar
Cherie LeFevre, M.D.
Associate Professor
Division of Urogynecology
    CURRENT RESEARCH ACTIVITY:
    Vulvovaginal Diseases:
  • Vulvodynia
  • Vulvar dystrophy
  • Management of lichen sclerosus with topical Triamcinolone
Mary T. McLennan, M.D.
Professor and Director, Urogynecology
Director, Residency Program
    CURRENT RESEARCH ACTIVITY:
  • Resident Education
  • Different techniques for tension free slings
  • Role of hydrodistension & interstitial cystitis
  • Role of estrogen in interstitial cystitis
Fah Che Leong, M.D.
Professor
Division of Urogynecology
    CURRENT RESEARCH ACTIVITY:
  • Peripheral sacral neuromodulation for urge incontinence, voiding dysfunction and pelvic pain
  • Lumbosacral dysfunction associated with pelvic pain
  • Treatment of interstitial cystitis
  • Myofascial pain
  • Treatment of overactive bladder
Kimberly Martin, M. D.
Assistant Professor
Division Maternal-Fetal Medicine
    CURRENT RESEARCH ACTIVITY:
  • Factors involved in obtaining Informed consent and facilitating decision making regarding testing for aneuploidy Prenatal diagnosis of birth defects
Thinh P. Nguyen, M. D.
Instructor, Clinical Educator Division Maternal-Fetal Medicine
    CURRENT RESEARCH ACTIVITY:
  • Simulation and education
  • Maternal medical disease in pregnancy
  • Genetics
  • Applications of technology in medicine
Andrew Steele, M.D.
Professor
Division of Urogynecology
    CURRENT RESEARCH ACTIVITY:
  • Pelvic floor anatomy
  • Vaginal mesh removal
  • Treatment of interstitial cystitis
  • Urinary incontinence
Pericles Xynos, M.D.
Instructor
Generalist Division
    CURRENT RESEARCH ACTIVITY:
  • complex GYN surgery
  • Advanced laparoscopy
Patrick Yeung Jr. M.D.
Assitant Professor
Director, Minimally Invasive Gynecology Surgery
    CURRENT RESEARCH ACTIVITY:
  • Predictive Factor for Difficulty of TLH
  • Prospective Study Comparing Disposable Vessel Sealing Device & Reusable Bipolar
  • Principal Investigator for a multi-step, multi-center trial to do a prospective randomized comparison of excision versus ablation in the laparoscopic management of endometriosis. Completing pilot study phase. Carried out through by the AAGL Research Committee.
  • Principal Investigator for creating a prospective database and tissue bank for the Saint Louis University Center for Endometriosis. This will be used to evaluate outcomes of excision for endometriosis, and to provide a mechanism to studying endometriosis samples to ultimately find a cure for endometriosis.
  • Site Investigator for a multi-center retrospective study looking at comparing two different classification systems for endometriosis - the old one (revised version of the American Society of Reproductive Medicine) and a new one (developed by a Special Interest group on Endometriosis of the American Association of Gynecologic Laparoscopists).
  • Site investigator for in a multi-center, randomized controlled trial of single site laparoscopic surgery versus conventional laparoscopic surgery for total hysterectomy. Sponsored by Covidien.
  • Supervising author for a study entitled Patient Preferences of Cosmesis for Incisions in Gynecologic Surgery. Manuscript in submission phase.
Donald Gregory Ward, M.D.
Assistant Professor
Director, Generalist Division
Co-Director Residency Program
    CURRENT RESEARCH ACTIVITY:
  • Correlation of Triage and Formal UTS
  • Infectious Disease
  • STD’s
  • Postmenopausal bleeding
  • Abnormal Uterine Bleeding
Mitul Shah, M.D.
Assistant Professor
Co-Director Residency Program
    CURRENT RESEARCH ACTIVITY:
  • Menopause and Female Sexual Disorders
  • Hypertension in Pregnancy as related to Body Mass Index
Leslie McCloskey, M.D.
Assistant Professor
Director, Colpo Clinic
Liaison County Clinics
    CURRENT RESEARCH ACTIVITY:
  • Outcomes of Low Risk Pregnancies with Spontaneous Decelerations in Triage
  • Abnormal Pap Smears
  • Colonoscopy
Diane Petersen, M.D.
Assistant Professor
Co-Director, Residency Program
    CURRENT RESEARCH ACTIVITY:
  • Endometrial Stripe in Women with and without Abnormal Uterine Bleeding
  • Postmenopausal women
  • Family Planning
  • Abnormal Pap Smears
Jill K. Powell, M.D.
Associate Professor
    CURRENT RESEARCH ACTIVITY:
  • Pediatric and Adolescent Gynecology
  • Gynecologic Care for Special Needs population
  • musculoskeletal causes of abdominal and pelvic pain

Jeff Gavard, Ph.D.
Assistant Professor & Biostatician
Research Division